Edodekin alfa
Edodekin alfa is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
267 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Crohn disease | D003424 | EFO_0000384 | K50 | 2 | 6 | 2 | 2 | 2 | 13 |
| Psoriasis | D011565 | EFO_0000676 | L40 | 1 | 7 | 3 | 2 | 1 | 12 |
| Sepsis | D018805 | HP_0100806 | A41.9 | — | — | 1 | 1 | 1 | 3 |
| Allergic rhinitis seasonal | D006255 | EFO_0003956 | J30 | — | — | — | 1 | 1 | 2 |
| Postoperative complications | D011183 | — | — | — | — | — | 1 | — | 1 |
| Impacted tooth | D014095 | HP_0011079 | K01.1 | — | — | — | 1 | — | 1 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | — | — | — | 1 | — | 1 |
| Allergic rhinitis | D065631 | — | J30.9 | — | — | — | 1 | — | 1 |
| Rhinitis | D012220 | EFO_0008521 | J31 | — | — | — | 1 | — | 1 |
| Endotoxemia | D019446 | — | — | — | — | — | 1 | — | 1 |
Show 2 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 35 | 9 | 1 | — | — | 39 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | 1 | 3 | 2 | — | 2 | 8 |
| Covid-19 | D000086382 | — | — | — | 1 | 3 | — | 3 | 7 |
| Infections | D007239 | EFO_0000544 | — | 4 | — | 2 | — | — | 6 |
| Psoriatic arthritis | D015535 | EFO_0003778 | L40.5 | — | 1 | 2 | — | 1 | 4 |
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | — | — | 2 | — | 2 | 4 |
| Communicable diseases | D003141 | — | — | 3 | — | 1 | — | — | 4 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 1 | 1 | — | 1 | 3 |
| Dermatitis | D003872 | HP_0011123 | L30.9 | — | 1 | 1 | — | 1 | 3 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | — | 2 | — | 1 | 3 |
Show 17 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 21 | 3 | — | — | 3 | 24 |
| Carcinoma | D002277 | — | C80.0 | 9 | 14 | — | — | — | 18 |
| Melanoma | D008545 | — | — | 9 | 10 | — | — | 1 | 18 |
| Recurrence | D012008 | — | — | 11 | 9 | — | — | — | 17 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 12 | 5 | — | — | — | 16 |
| Lymphoma | D008223 | — | C85.9 | 6 | 8 | — | — | — | 13 |
| Colorectal neoplasms | D015179 | — | — | 10 | 4 | — | — | — | 12 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 9 | 4 | — | — | — | 10 |
| Sarcoma | D012509 | — | — | 6 | 5 | — | — | 1 | 10 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 8 | 6 | — | — | — | 10 |
Show 112 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Immunologic deficiency syndromes | D007153 | HP_0002721 | D84.9 | 2 | — | — | — | 3 | 5 |
| Adenocarcinoma | D000230 | — | — | 3 | — | — | — | — | 3 |
| Esophageal neoplasms | D004938 | — | C15 | 3 | — | — | — | — | 3 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 2 | — | — | — | — | 2 |
| Germ cell and embryonal neoplasms | D009373 | — | — | 2 | — | — | — | — | 2 |
| Male breast neoplasms | D018567 | — | — | 2 | — | — | — | — | 2 |
| Gallbladder neoplasms | D005706 | EFO_0004606 | C23 | 2 | — | — | — | — | 2 |
| Neuroblastoma | D009447 | EFO_0000621 | — | 2 | — | — | — | — | 2 |
| Mycobacterium infections | D009164 | — | A31.9 | 2 | — | — | — | — | 2 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 2 | — | — | — | — | 2 |
Show 63 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | — | — | — | 3 | 3 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | — | — | 2 | 2 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 2 | 2 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 2 | 2 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | — | — | 1 | 1 |
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | — | — | 1 | 1 |
| Coronary disease | D003327 | — | — | — | — | — | — | 1 | 1 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | — | — | 1 | 1 |
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | — | — | — | — | 1 | 1 |
| Shock | D012769 | — | R57.1 | — | — | — | — | 1 | 1 |
Show 23 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Edodekin alfa |
| INN | edodekin alfa |
| Description | Edodekin alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | interleukins: interleukin-12 analogues and derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109059 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 31Z82G8ME1 (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Additional graphs summarizing 14 documents
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Safety
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Adverse Events
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13 adverse events reported
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